God knows why a press release wouldn't provide a direct link
보도자료에 직접 링크가 없는 이유를 모르겠음.
Other features of the vaccine were also promising, most notably how the crucial immune cells remained in a state of development that allowed them to continue acquiring mutations, so they could evolve along with the ever-changing virus.
백신의 다른 특징들도 유망함. 특히 중요한 면역 세포들이 계속 변이를 획득할 수 있는 상태로 남아 있어, 변화하는 바이러스와 함께 진화할 수 있음.
As I understand it, somatic hypermutation is a process that only occurs within germinal centers.
Very promising outcome. But I wonder they/why we are just learning about this now when it seems that the inoculations occurred in 2017?
매우 유망한 결과임. 하지만 접종이 2017년에 이루어진 것 같은데 왜 이제야 이 사실을 알게 되었는지 궁금함.
Perhaps this could be a beneficial prophylaxis. And having another treatment that uses CRISPR to remove the provirus is also an essential to have a durable cure for patients already infected.
이것이 유익한 예방책이 될 수 있을 것임. 또한 CRISPR를 사용하여 프로바이러스를 제거하는 또 다른 치료법을 갖는 것도 이미 감염된 환자들에게 지속 가능한 치료법을 제공하는 데 필수적임.
I'm not an expert on this stuff at all, so assume I'm stupid and ignorant when I write the following. As I understand it, HIV has actually been useful to develop a delivery mechanism for some therapies that have excellent potential. Would this kind of vaccine cause such therapies to become ineffective?
나는 이 분야의 전문가가 아니므로 내가 쓰는 다음 내용을 무지하다고 생각해주길 바람. 내가 이해하기로는 HIV가 실제로 잠재력이 뛰어난 일부 치료법의 전달 메커니즘을 개발하는 데 유용했음. 이런 종류의 백신이 그러한 치료법을 무효화할 수 있을까?
I am not an immunologist... I don't understand biology very well. How significant is this? Is it even trustworthy?
나는 면역학자가 아님... 생물학을 잘 이해하지 못함. 이것이 얼마나 중요한가? 신뢰할 만한가?
Does this university press release name-check Cell but not link to the article? A bit frustrating.
이 대학 보도자료가 Cell을 언급하면서도 기사 링크는 제공하지 않는가? 약간 답답함.
I wonder about the potential for varied immune responses across different populations.
Hacker News 의견
해커뉴스 댓글 모음
Animation of how HIV infects a single T-cell
Actual paper is here:
God knows why a press release wouldn't provide a direct link
Other features of the vaccine were also promising, most notably how the crucial immune cells remained in a state of development that allowed them to continue acquiring mutations, so they could evolve along with the ever-changing virus.
As I understand it, somatic hypermutation is a process that only occurs within germinal centers.
Is that what is happening here?
Here is the Cell article:
Very promising outcome. But I wonder they/why we are just learning about this now when it seems that the inoculations occurred in 2017?
Perhaps this could be a beneficial prophylaxis. And having another treatment that uses CRISPR to remove the provirus is also an essential to have a durable cure for patients already infected.
I'm not an expert on this stuff at all, so assume I'm stupid and ignorant when I write the following. As I understand it, HIV has actually been useful to develop a delivery mechanism for some therapies that have excellent potential. Would this kind of vaccine cause such therapies to become ineffective?
I am not an immunologist... I don't understand biology very well. How significant is this? Is it even trustworthy?
Does this university press release name-check Cell but not link to the article? A bit frustrating.
I wonder about the potential for varied immune responses across different populations.